Thursday, April 25, 2013

Modelling Reveals Likely Spread of New H7N9 Avian Flu

This new one, by all indications is no spring flu. This one kills, and if it does start spreading between humans directly, we are in trouble.

Yeah, that's what they said about H5N1, and a million different viruses and diseases that were the disease-of-the-moment before that, going back decades (remember the Russian Flu, anyone?). A bunch of epidemiologists get a lot of grant money, news channels get some ratings from the disease-of-the-moment, the public overreacts like they always do, much bullshit is spoken, and a year or two later it's on to the next goddamned thing that's going to KILL US ALL!

And before you cite 1918 (as is ALWAYS cited in th

Source: http://rss.slashdot.org/~r/Slashdot/slashdotScience/~3/lyFM3XPs73k/story01.htm

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Exclusive: Verizon eyes roughly $100 billion bid for Vodafone's wireless stake

By Soyoung Kim and Kate Holton

NEW YORK/LONDON (Reuters) - Verizon Communications has hired advisers to prepare a possible $100 billion bid to take full control of Verizon Wireless from its partner Vodafone, two people familiar with the matter said.

The two sources said Verizon was considering a 50:50 cash and stock bid for the 45 percent stake it does not already own, an asset it has long coveted but that Vodafone will take some persuading to give up. It has not put a proposal to Vodafone yet but has hired both banking and legal advisers for a possible offer, the sources said.

Vodafone investors and analysts said the $100 billion figure was too low and more of an opening gambit to bring the British firm to the table. Shares in Vodafone, the world's second largest mobile operator, were up 2.6 percent at 198 pence.

"I'd be delighted with $135 billion, but there's absolutely no way it will be $100 billion," one top 40 Vodafone investor said on condition of anonymity. "The guidance I have had from someone close to the company is that they are looking at $125-130 billion."

Verizon, which has made little secret of its wish to buy out its British partner from the biggest U.S. mobile operator, has ramped up the pressure in recent months, saying publicly that it believed it could buy the asset in a tax-efficient way.

The two sides have previously held high-level talks to discuss options that ranged from a stake sale to a full merger and how any deal could avoid incurring a possible $20 billion capital gains tax for Vodafone, another person familiar with the situation has told Reuters.

The two sources who spoke to Reuters late on Wednesday said any deal would be structured such that the eventual tax bill would likely be $5 billion or less.

The two sources said Verizon was now ready to push more aggressively. It hopes to start discussions with Vodafone soon for a friendly agreement but is prepared to take a bid public if the British company does not engage, one of the sources added.

"I don't really see this as a surprise," one of Vodafone's 15 largest investors told Reuters, on condition of anonymity. "The talk about this deal has been quite intense recently.

"They should look to return a large amount to shareholders, retaining a relatively small amount for deleveraging and bolt-on deals. I don't think shareholders would be pleased with Vodafone viewing any disposal proceeds as an acquisition war chest."

Vodafone Chief Executive Vittorio Colao has so far said he has an open mind on whether to sell the group's 45 percent stake, which has come to make up around 75 percent of the firm's value in recent years as its core European business suffered.

Some analysts believe the Italian, who has won praise for his dealmaking in almost five years at the top of the group, could try to hold on to the asset for a little longer, until he sees some sign that his core European businesses are starting to stabilize.

But Colao will also know that the U.S. market could become more competitive due to a wave of consolidation, so he could decide that it might soon be the right time to walk away.

"The tax problem has always been the issue. If a way can be found around that, then it is highly likely that a deal will be done," the top-15 investor said.

Another way to avoid the tax issue would be for the two parent groups to merge, but Verizon said earlier this month that it was not looking to buy or merge with its partner.

Verizon, which is benefiting from record low interest rates as well as its own strong stock price, is instead confident that the company can raise about $50 billion of bank financing, the sources said. It plans to pay for the rest of the deal with its own shares, they added. The sources asked not to be named because the discussions are confidential.

BOARD ACTIVITY

Verizon's board is expected to discuss details of a potential Verizon Wireless buyout next week at a regularly scheduled meeting being held ahead of the company's annual shareholder meeting, one of the sources said.

Verizon spokesman Bob Varettoni declined to comment, but pointed to the U.S. telephone company's statement earlier this month, in which it said it would be a willing buyer of Vodafone's share of their Verizon Wireless venture.

Vodafone declined to comment.

Analysts have said a sale of Verizon Wireless would enable Vodafone to return cash to shareholders, purchase fixed-line assets in Europe or potentially make the company an attractive takeover target for other telecom giants such as AT&T Inc.

Shares in Vodafone have risen 26 percent this year on speculation that it could finally be ready to sell its stake, but most analysts had put the value of the Vodafone holding at nearer $120 billion.

Taking full ownership would give Verizon, which is reliant on the unit for growth, a lot more flexibility with the cash generated from the wireless business.

Analyst Jonathan Chaplin at New Street Research, said a deal at $100 billion would boost Verizon's earnings per share in 2014 by 33 percent.

"We doubt that Vodafone management or shareholders would be willing to sell for $100 billion; however, this is a good starting point for negotiations," he said in a note. "We believe a deal could be struck that would create significant value for both sets of shareholders."

Verizon came close to doing a deal in 2004, when Vodafone tried to buy AT&T Wireless but lost the auction to Cingular. That deal would have allowed Vodafone to bring its brand across the Atlantic and would have required it to sell its 45 percent stake in Verizon Wireless.

Any deal now, if it were to happen, would come at a time when the telecommunications industry is undergoing a fresh round of consolidation activity. MetroPCS Communications Inc shareholders voted on Wednesday to approve a merger with No.4 U.S. wireless service provider T-Mobile USA, a unit of Deutsche Telekom AG.

An earlier attempt by Deutsche Telekom to sell T-Mobile to AT&T for $39 billion in 2011 was blocked by U.S. antitrust regulators. Verizon would be unlikely to face any such obstacles in a Verizon Wireless buyout.

Meanwhile, Dish Network Corp, the No.2 U.S. satellite TV provider, last week offered to buy wireless service provider Sprint Nextel Corp for $25.5 billion in cash and stock, challenging a proposed deal between Sprint and Japan's SoftBank Corp.

Verizon's shares have risen about 20 percent so far this year as Wireless has been easily outperforming its smaller rivals in terms of profitability and customer growth, and on rising hopes of a buyout.

Verizon shares are valued at 17.9 times forward earnings, compared with 11.8 for Vodafone.

(Reporting By Soyoung Kim and Sinead Carew in New York, and by Kate Holton and Sinead Cruise in London.; Editing by Paritosh Bansal, Martin Howell and Will Waterman)

Source: http://news.yahoo.com/exclusive-verizon-eyes-roughly-100-billion-bid-verizon-015353243--sector.html

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Jeb Bush Is Cleaning Out His Closet for 2016

Have enough Americans forgiven George W. Bush that they'll vote for his brother for president??Jeb Bush is doing several things that indicate he thinks so. He gave a speech in Dallas Wednesday titled "Restoring America's Promise: The Leadership Required and the Policy Changes that are Needed." He wrote a book about immigration reform. He's giving speeches about education. Oh, and he's getting potentially embarrassing news out of the way. Bush's maid was deported in 1991, The Washington Post's Manuel Roig-Franzia and Peter Wallsten report Wednesday. "It was a difficult time for all of us, but most of all for Maria," Bush told the newspaper.

RELATED: The 2016 Guessing Game Needs to End

Bush and his wife Columba could not stop the deportation, even though Bush's dad was president at the time, the?Post reports. Jeb Jr. was just 10, and didn't know she was deported. "I thought she just left," Jeb Jr. says. The Post is clear about what Bush's experience means: "While Republicans cast about for leaders who can connect with Spanish-speaking voters, this tall Texas native with the Mexican American wife has remarkably come to represent a kind of Hispanic consciousness for the party."?Bush has experience with bigotry. When his son was playing a baseball game in seventh grade, someone in the stands yelled out a slur for Hispanic. "His skin is darker, because my wife is from Mexico," Bush said at a 1998 campaign stop. "He has been discriminated against... This was my family. There is hatred out there."

RELATED: Let's Talk About a Potential Bush in 2016

Earlier this month, George W. Bush told?Parade magazine, "I hope he will run."?Politico's Anna Palmer reports that Bush has the things he needs to be elected president: "money, r?sum? and connections." Alas, "he's also got a problem: his last name." Former Republican National Committee chair Haley Barbour said, "I would put it this way ? if Jeb's last name was Brown instead of Bush, he?d probably be the front-runner for the Republican nomination." The idea that the only thing holding Bush back is his name has been around since at least 2007, and has been?repeated?many?times. But if Bush's last name were Brown, we probably would have never heard of him. In 1994, the?Palm Beach Post?complained that Bush's "political?r?sum??begins and ends with his last name." Will he run in 2016? Bush said Wednesday, "To be honest with you, I'm focused on the land commissioner race in 2014." That would be the race featuring his son, George P. Bush, who will be in attendance at the dedication of the?George W. Bush Presidential Center in Dallas Thursday ? along with his brother, his father, and President Obama, as well as former President Bill Clinton... and his wife.

Source: http://news.yahoo.com/jeb-bush-cleaning-closet-2016-191802685.html

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Samsung?s enterprise ambitions put on hold as KNOX security software delayed

MADRID, April 25 (Reuters) - Liverpool goalkeeper Pepe Reina said the 10-match ban given to his team mate Luis Suarez for biting an opponent was 'absurd' and 'excessive'. Uruguay international Suarez was punished on Wednesday by the English Football Association (FA) after he bit the arm of Chelsea defender Branislav Ivanovic at the weekend. "He knows he is in the wrong, and that it was a mistake, but the 10-game punishment seems absurd to me, excessive and unfair," Spanish international Reina was quoted as telling radio station Cadena Cope by sports daily AS on Thursday. ...

Source: http://news.yahoo.com/samsung-enterprise-ambitions-put-hold-knox-security-software-231038568.html

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BlackBerry Q10 review

DNP BlackBerry Q10 review

You can't please everybody all the time, and if there's a company who knows this better than the rest, it's BlackBerry. At the showy launch for BlackBerry 10, the company finally unveiled its new stable of smartphones with which it would fight the likes of Apple, Samsung, HTC, Microsoft, Nokia and Google. No simple task, that, and so BlackBerry rolled out not one, but two weapons: the all-touch Z10 and the portrait-QWERTY Q10.

But there was a catch: only one would launch at a time. It was a staged attack, with the Z10 forming the initial volley. This, many said, was a mistake, and that the Q10 and its familiar physical keyboard should have gone first, paving the way for the more radical, all-touch Z10. After what seems like an eternity, the $249 BlackBerry Q10 is finally ready for duty, so let's put it through its paces and see which of these fraternal twins is truly the flagship.

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Source: http://www.engadget.com/2013/04/23/blackberry-q10-review/?utm_medium=feed&utm_source=Feed_Classic&utm_campaign=Engadget

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Discovery of new genes will help childhood arthritis treatment

Tuesday, April 23, 2013

Scientists from The University of Manchester have identified 14 new genes which could have important consequences for future treatments of childhood arthritis. Scientists Dr Anne Hinks, Dr Joanna Cobb and Professor Wendy Thomson, from the University's Arthritis Research UK Epidemiology Unit, whose work is published in Nature Geneticsyesterday, looked at DNA extracted from blood and saliva samples of 2,000 children with childhood arthritis and compared these to healthy people.

Principal Investigator Professor Thomson, who also leads the Inflammatory Arthritis in Children theme at the National Institute for Health Research (NIHR) Manchester Musculoskeletal Biomedical Research Unit, said: "This study brought together an international group of scientists from around the world and is the largest investigation into the genetics of childhood arthritis to date."

Childhood arthritis affects one in 1,000 in the UK. It is caused by a combination of genetic and environmental risk factors, however until recently very little was known about the genes that are important in developing this disease ? only three were previously known.

Dr Hinks, joint lead author of the study, said the findings were significant for understanding more about the biology of the disease and this might help identify novel therapies for the disease. "Childhood arthritis, also known as juvenile idiopathic arthritis (JIA), is a specific type of arthritis quite separate from types found in adults and there's been only a limited amount of research into this area in the past," she said. "This study set out to look for specific risk factors. To identify these 14 genetic risk factors is quite a big discovery. It will help us to understand what's causing the condition, how it progresses and then to potentially develop new therapies."

The study may help to predict which children need specific treatment earlier and allow health workers to better control their pain management, quality of life and long-term outcome. Currently 30 per cent of children with the disease continue to suffer from arthritis in adulthood.

Dr Cobb, joint lead author, added: "There are lots of different forms of childhood arthritis so identifying the markers will help us understand a little bit more about the disease process. It will also help to categorise children with JIA into sub-types dependent on which genes they have and allow us to determine the best course of treatment."

The study which took two years to complete, will ultimately help clinicians to better manage children with the disease and give potential to develop new therapies.

Professor Alan Silman, medical director of Arthritis Research UK who part funded the work, said: "We have known for some time that there is a strong genetic contribution to a child's risk of developing JIA, however previously only three genetic risk factors had been identified. This study is the largest genetic investigation of JIA to date and has identified 14 new risk regions, adding a significant amount to our knowledge of the genetic basis of this disorder. Further work is now required to investigate each of these regions in more detail, to enable us to understand how they are involved in disease development and identify potential new therapeutic targets."

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University of Manchester: http://www.manchester.ac.uk

Thanks to University of Manchester for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/127864/Discovery_of_new_genes_will_help_childhood_arthritis_treatment

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RI lawmakers to vote on gay marriage

PROVIDENCE, R.I. (AP) ? State lawmakers in Rhode Island could decide whether the nation's smallest state becomes the 10th to allow gay and lesbian couples to marry.

Following months of review and debate, the state Senate is set to vote on gay marriage legislation Wednesday afternoon. The bill easily passed the House in January and has the support of independent Gov. Lincoln Chafee.

Gay marriage legislation has been introduced in Rhode Island's General Assembly for nearly two decades only to languish on the legislative agenda. Heavily Catholic Rhode Island is now the only state in New England that does not allow same-sex couples to marry. Gay marriage is law in nine states and the District of Columbia.

Wednesday's vote comes after the Senate Judiciary Committee voted 7-4 Tuesday to forward the legislation to the Senate floor. Dozens of supporters cheered and cried following the vote. Ken Fish, a 70-year-old gay man from Warwick, said he watched the committee vote with a mixture of disbelief and elation.

"It's almost unreal to think we're here, after all these years," he said. "I wasn't sure we'd ever get here."

If the bill passes the Senate it must return to the House for a largely procedural vote on small changes made to the bill on the Senate side. House Speaker Gordon Fox, D-Providence, said a final vote could come as early as next week.

Support for the bill has grown since it passed the House in January. On Tuesday, the Senate's five Republicans announced they would all support the legislation, further improving the bill's chances.

"We've got one more step, but I expect it to pass with overwhelming support," said Sen. Dawson Hodgson, R-North Kingstown.

Opponents aren't giving up on efforts to turn back the legislation. Sen. Harold Metts, D-Providence, said he planned to fast and pray ahead of Wednesday's debate.

"Culture may change, but God has an immutable character," he said. "I'll be praying all night."

Chafee encouraged supporters to contact their senators ahead of the vote but signaled that he thinks the bill will pass, saying in a statement that "I believe that when the roll is called, marriage equality will become law in Rhode Island."

The Senate has long been seen as the true test for gay marriage in Rhode Island. Two years ago, gay marriage legislation languished after it became apparent it would be defeated in the Senate. Senate President Teresa Paiva Weed, D-Newport, opposes the bill but has vowed not to obstruct debate.

The Rhode Island legislation states that religious institutions may set their own rules for who is eligible to marry within their faith and specifies that no religious leader is obligated to officiate at any marriage ceremony. While ministers already cannot be forced to marry anyone, the exemption helped assuage concerns from some lawmakers that clergy could face lawsuits for abiding by their religious convictions.

Source: http://news.yahoo.com/ri-lawmakers-vote-gay-marriage-062021344.html

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